An old friend with a new face: YB-1 and its role in healthy pregnancy and pregnancy-associated complications

An old friend with a new face: YB-1 and its role in healthy pregnancy and pregnancy-associated complications

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By promoting tissue invasion, cell growth and angiogenesis, the Y-box binding protein (YB-1) became famous as multifunctional oncoprotein.However, this designation is telling only part of the story.There is one particular time in life when actual tumorigenic-like processes become undoubtedly Sneakers for Men - Grey - Canvas Mesh Athletic Running Shoes welcome, namely pregnancy.

It seems therefore reasonable that YB-1 plays also a crucial role in reproduction, and yet this biological aspect of the cold-shock protein has been overlooked for many years.To overcome turbosound ts-18sw700/8a this limitation, we would like to propose a new perspective on YB-1 and emphasize its pivotal functions in healthy pregnancy and pregnancy-related complications.Moreover, we will discuss findings obtained from cancer research in the light of reproductive events to elucidate the importance of YB-1 at the feto-maternal interface.